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                  Tips for Increasing Transfection Efficiency Chemical transfection , which relies on the formation of a condensed complex of positively charged  liposomal or non-liposomal  reagents and negatively charged nucleic acids, is the most common method for delivering foreign genetic material into cultured cells. Complexes are attracted to the negatively charged cell membrane and potentially pass through it via mechanisms involving endocytosis and phagocytosis. 1 “The negative to positive ratio impacts the complex size and the overall positive charge. The best ratio is cell type dependent,” says  Sandy Tseng, PhD,   technical support scientist, Mirus Bio. Chemical methods offer a slew of advantages: relatively low cytotoxicity, ease of use, cost effectiveness, low likelihood for unintended mutagenesis , no viral vector involvement, no discrimination of type of nucleic acid, and researcher safety. Bu...

Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C                                                                                                                                                                        In a recent study posted to the medrivix pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and  multisysteminflammatory syndrome in children  (MIS-C) to inform future development of novel biomarkers for both diseases.   B...

27th World Congress on Industrial Biotechnology   The organising team extends its warmest greetings! Following the tremendous success of the 27th World Congress on Industrial Biotechnology , we are delighted to extend an invitation to all eminent scientists, young researchers, academicians, business delegates, previous congress attendees, and students from all over the world to attend the 27th World Congress on Industrial Biotechnology, which will be held November 16-17, 2022 in Tokyo, Japan. It is an international gathering to present and discuss advances in Industrial Biotechnology-based research, techniques, frameworks, innovations, standards, and applications of themes linked to the field. The congress will undoubtedly benefit scholars and practitioners in this field. The conference will feature a number of illustrious speakers who will present their most recent research findings that will transform the field of industrial biotechnology in the future. Industrial Biotechnology20...